The Magellan eXplorist line of GPS units. Instead of having to type in a waypoint, the explorist units have a number of geocaches in the unit already. The Explorist 610 even has Turn by turn directions up to the nearest road and then walking point-to-point directions for the hike to the cache. Some models even have a camera so you can take a picture of the waypoint instead of typing it in manually.
More information can be found at magellangps.com